GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6037105 | chr20:25374199 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.06E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037105 | chr20:25374199 | NINL | chr20:25433338-25566153:- | 0.33 | 6.9 | 1.7E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037105 | chr20:25374199 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.5E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037121 | chr20:25428311 | ENTPD6 | chr20:25176339-25207360:+ | -0.32 | -7.43 | 5.05E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037121 | chr20:25428311 | FAM182A | chr20:26035250-26067552:+ | -0.18 | -3.44 | 0.000635 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037121 | chr20:25428311 | FAM182B | chr20:25744102-25848786:- | 0.25 | 5.25 | 2.3E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037121 | chr20:25428311 | NINL | chr20:25433338-25566153:- | -0.34 | -7.11 | 4.29E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037121 | chr20:25428311 | PYGB | chr20:25228706-25278647:+ | -0.15 | -3.78 | 0.000174 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs965469 | 1 | rs6037526 | chr20:3251248 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.87 | 8.02E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6037532 | chr20:3267911 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.92 | 6.32E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6037533 | chr20:3268817 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.92 | 6.32E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6037535 | chr20:3270621 | ITPA | chr20:3190056-3204504:+ | -0.25 | -6.07 | 2.6E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6037538 | chr20:3282978 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.88 | 7.83E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6037547 | chr20:3299228 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.87 | 8.02E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6037551 | chr20:3306690 | ITPA | chr20:3190056-3204504:+ | -0.25 | -6.07 | 2.6E-9 | IFN-related cytopenia |